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Testo: <blockquote data-quote="sepica" data-source="post: 7321201" data-attributes="member: 2116"><p>In the present study, we found that a single ingestion of 6 g of L-citrulline 1 hour before resistive breathing significantly increased NO• bioavailability. Considering the strong ergogenic effects that NO• has on exercise performance, this observation is of utmost importance for acute L-citrulline ingestion 1 hour before exercise events. However, neither respiratory muscle performance and resistance to fatigue nor sternocleidomastoid muscle oxygenation and deoxygenation responses were enhanced. These results imply that other reasons than NO• bioavailability might affect sternocleidomastoid muscle performance and blood flow during resistive breathing to task failure of the inspiratory muscles. In our opinion, L-citrulline supplementation is worthy of further consideration from the scientific community, especially in patients with cardiovascular or pulmonary diseases (e.g., lower-extremity artery disease, chronic obstructive pulmonary disease) that are usually characterized by insufficiently blood flow and oxygen delivery to the muscles. It would also be interesting for future studies to examine the effect of short-term (e.g., 7-day) supplementation with L-citrulline on inspiratory muscles performance and oxygenation.</p></blockquote><p></p>

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